League’s forum boards posted a fix a few months ago that still works with the current problem on Windows 10. When I open the launcher the cursor is in the password field, however when you tab away and back the cursor is gone. It seems not to register the key strokes from KeePass. However for the League of Legends Game launcher I won't get it to work.
Riot’s League of Legends often has bug splat errors and can crash the game, but with the new Windows 10 installment, players are getting a black screen and are unable to launch the game properly. I downloaded and got KeePass to work for everything until now. With the new installation of the hyped Windows 10, some people might come across a few compatibility issues with their games.